1 Introduction to Research & Analysis Reports
1.1 Single Plane Illumination Microscopy Market Definition
1.2 Market Segments
1.2.1 Market by Type
1.2.2 Market by Application
1.3 Global Single Plane Illumination Microscopy Market Overview
1.4 Features & Benefits of This Report
1.5 Methodology & Sources of Information
1.5.1 Research Methodology
1.5.2 Research Process
1.5.3 Base Year
1.5.4 Report Assumptions & Caveats
2 Global Single Plane Illumination Microscopy Overall Market Size
2.1 Global Single Plane Illumination Microscopy Market Size: 2022 VS 2029
2.2 Global Single Plane Illumination Microscopy Revenue, Prospects & Forecasts: 2018-2029
2.3 Global Single Plane Illumination Microscopy Sales: 2018-2029
3 Company Landscape
3.1 Top Single Plane Illumination Microscopy Players in Global Market
3.2 Top Global Single Plane Illumination Microscopy Companies Ranked by Revenue
3.3 Global Single Plane Illumination Microscopy Revenue by Companies
3.4 Global Single Plane Illumination Microscopy Sales by Companies
3.5 Global Single Plane Illumination Microscopy Price by Manufacturer (2018-2023)
3.6 Top 3 and Top 5 Single Plane Illumination Microscopy Companies in Global Market, by Revenue in 2022
3.7 Global Manufacturers Single Plane Illumination Microscopy Product Type
3.8 Tier 1, Tier 2 and Tier 3 Single Plane Illumination Microscopy Players in Global Market
3.8.1 List of Global Tier 1 Single Plane Illumination Microscopy Companies
3.8.2 List of Global Tier 2 and Tier 3 Single Plane Illumination Microscopy Companies
4 Sights by Product
4.1 Overview
4.1.1 By Type – Global Single Plane Illumination Microscopy Market Size Markets, 2022 & 2029
4.1.2 Wide Field Microscopy
4.1.3 Confocal Microscopy
4.1.4 Others
4.2 By Type – Global Single Plane Illumination Microscopy Revenue & Forecasts
4.2.1 By Type – Global Single Plane Illumination Microscopy Revenue, 2018-2023
4.2.2 By Type – Global Single Plane Illumination Microscopy Revenue, 2024-2029
4.2.3 By Type – Global Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
4.3 By Type – Global Single Plane Illumination Microscopy Sales & Forecasts
4.3.1 By Type – Global Single Plane Illumination Microscopy Sales, 2018-2023
4.3.2 By Type – Global Single Plane Illumination Microscopy Sales, 2024-2029
4.3.3 By Type – Global Single Plane Illumination Microscopy Sales Market Share, 2018-2029
4.4 By Type – Global Single Plane Illumination Microscopy Price (Manufacturers Selling Prices), 2018-2029
5 Sights by Application
5.1 Overview
5.1.1 By Application – Global Single Plane Illumination Microscopy Market Size, 2022 & 2029
5.1.2 Developmental Biology
5.1.3 Nephrology
5.1.4 Neuronal Morphology
5.1.5 Immunology
5.1.6 Others
5.2 By Application – Global Single Plane Illumination Microscopy Revenue & Forecasts
5.2.1 By Application – Global Single Plane Illumination Microscopy Revenue, 2018-2023
5.2.2 By Application – Global Single Plane Illumination Microscopy Revenue, 2024-2029
5.2.3 By Application – Global Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
5.3 By Application – Global Single Plane Illumination Microscopy Sales & Forecasts
5.3.1 By Application – Global Single Plane Illumination Microscopy Sales, 2018-2023
5.3.2 By Application – Global Single Plane Illumination Microscopy Sales, 2024-2029
5.3.3 By Application – Global Single Plane Illumination Microscopy Sales Market Share, 2018-2029
5.4 By Application – Global Single Plane Illumination Microscopy Price (Manufacturers Selling Prices), 2018-2029
6 Sights by Region
6.1 By Region – Global Single Plane Illumination Microscopy Market Size, 2022 & 2029
6.2 By Region – Global Single Plane Illumination Microscopy Revenue & Forecasts
6.2.1 By Region – Global Single Plane Illumination Microscopy Revenue, 2018-2023
6.2.2 By Region – Global Single Plane Illumination Microscopy Revenue, 2024-2029
6.2.3 By Region – Global Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
6.3 By Region – Global Single Plane Illumination Microscopy Sales & Forecasts
6.3.1 By Region – Global Single Plane Illumination Microscopy Sales, 2018-2023
6.3.2 By Region – Global Single Plane Illumination Microscopy Sales, 2024-2029
6.3.3 By Region – Global Single Plane Illumination Microscopy Sales Market Share, 2018-2029
6.4 North America
6.4.1 By Country – North America Single Plane Illumination Microscopy Revenue, 2018-2029
6.4.2 By Country – North America Single Plane Illumination Microscopy Sales, 2018-2029
6.4.3 US Single Plane Illumination Microscopy Market Size, 2018-2029
6.4.4 Canada Single Plane Illumination Microscopy Market Size, 2018-2029
6.4.5 Mexico Single Plane Illumination Microscopy Market Size, 2018-2029
6.5 Europe
6.5.1 By Country – Europe Single Plane Illumination Microscopy Revenue, 2018-2029
6.5.2 By Country – Europe Single Plane Illumination Microscopy Sales, 2018-2029
6.5.3 Germany Single Plane Illumination Microscopy Market Size, 2018-2029
6.5.4 France Single Plane Illumination Microscopy Market Size, 2018-2029
6.5.5 U.K. Single Plane Illumination Microscopy Market Size, 2018-2029
6.5.6 Italy Single Plane Illumination Microscopy Market Size, 2018-2029
6.5.7 Russia Single Plane Illumination Microscopy Market Size, 2018-2029
6.5.8 Nordic Countries Single Plane Illumination Microscopy Market Size, 2018-2029
6.5.9 Benelux Single Plane Illumination Microscopy Market Size, 2018-2029
6.6 Asia
6.6.1 By Region – Asia Single Plane Illumination Microscopy Revenue, 2018-2029
6.6.2 By Region – Asia Single Plane Illumination Microscopy Sales, 2018-2029
6.6.3 China Single Plane Illumination Microscopy Market Size, 2018-2029
6.6.4 Japan Single Plane Illumination Microscopy Market Size, 2018-2029
6.6.5 South Korea Single Plane Illumination Microscopy Market Size, 2018-2029
6.6.6 Southeast Asia Single Plane Illumination Microscopy Market Size, 2018-2029
6.6.7 India Single Plane Illumination Microscopy Market Size, 2018-2029
6.7 South America
6.7.1 By Country – South America Single Plane Illumination Microscopy Revenue, 2018-2029
6.7.2 By Country – South America Single Plane Illumination Microscopy Sales, 2018-2029
6.7.3 Brazil Single Plane Illumination Microscopy Market Size, 2018-2029
6.7.4 Argentina Single Plane Illumination Microscopy Market Size, 2018-2029
6.8 Middle East & Africa
6.8.1 By Country – Middle East & Africa Single Plane Illumination Microscopy Revenue, 2018-2029
6.8.2 By Country – Middle East & Africa Single Plane Illumination Microscopy Sales, 2018-2029
6.8.3 Turkey Single Plane Illumination Microscopy Market Size, 2018-2029
6.8.4 Israel Single Plane Illumination Microscopy Market Size, 2018-2029
6.8.5 Saudi Arabia Single Plane Illumination Microscopy Market Size, 2018-2029
6.8.6 UAE Single Plane Illumination Microscopy Market Size, 2018-2029
7 Manufacturers & Brands Profiles
7.1 Zesis
7.1.1 Zesis Company Summary
7.1.2 Zesis Business Overview
7.1.3 Zesis Single Plane Illumination Microscopy Major Product Offerings
7.1.4 Zesis Single Plane Illumination Microscopy Sales and Revenue in Global (2018-2023)
7.1.5 Zesis Key News & Latest Developments
7.2 Miltenyi Biotec
7.2.1 Miltenyi Biotec Company Summary
7.2.2 Miltenyi Biotec Business Overview
7.2.3 Miltenyi Biotec Single Plane Illumination Microscopy Major Product Offerings
7.2.4 Miltenyi Biotec Single Plane Illumination Microscopy Sales and Revenue in Global (2018-2023)
7.2.5 Miltenyi Biotec Key News & Latest Developments
7.3 Bruker
7.3.1 Bruker Company Summary
7.3.2 Bruker Business Overview
7.3.3 Bruker Single Plane Illumination Microscopy Major Product Offerings
7.3.4 Bruker Single Plane Illumination Microscopy Sales and Revenue in Global (2018-2023)
7.3.5 Bruker Key News & Latest Developments
7.4 Leica
7.4.1 Leica Company Summary
7.4.2 Leica Business Overview
7.4.3 Leica Single Plane Illumination Microscopy Major Product Offerings
7.4.4 Leica Single Plane Illumination Microscopy Sales and Revenue in Global (2018-2023)
7.4.5 Leica Key News & Latest Developments
7.5 Nuohai
7.5.1 Nuohai Company Summary
7.5.2 Nuohai Business Overview
7.5.3 Nuohai Single Plane Illumination Microscopy Major Product Offerings
7.5.4 Nuohai Single Plane Illumination Microscopy Sales and Revenue in Global (2018-2023)
7.5.5 Nuohai Key News & Latest Developments
8 Global Single Plane Illumination Microscopy Production Capacity, Analysis
8.1 Global Single Plane Illumination Microscopy Production Capacity, 2018-2029
8.2 Single Plane Illumination Microscopy Production Capacity of Key Manufacturers in Global Market
8.3 Global Single Plane Illumination Microscopy Production by Region
9 Key Market Trends, Opportunity, Drivers and Restraints
9.1 Market Opportunities & Trends
9.2 Market Drivers
9.3 Market Restraints
10 Single Plane Illumination Microscopy Supply Chain Analysis
10.1 Single Plane Illumination Microscopy Industry Value Chain
10.2 Single Plane Illumination Microscopy Upstream Market
10.3 Single Plane Illumination Microscopy Downstream and Clients
10.4 Marketing Channels Analysis
10.4.1 Marketing Channels
10.4.2 Single Plane Illumination Microscopy Distributors and Sales Agents in Global
11 Conclusion
12 Appendix
12.1 Note
12.2 Examples of Clients
12.3 Disclaimer
Table 1. Key Players of Single Plane Illumination Microscopy in Global Market
Table 2. Top Single Plane Illumination Microscopy Players in Global Market, Ranking by Revenue (2022)
Table 3. Global Single Plane Illumination Microscopy Revenue by Companies, (US$, Mn), 2018-2023
Table 4. Global Single Plane Illumination Microscopy Revenue Share by Companies, 2018-2023
Table 5. Global Single Plane Illumination Microscopy Sales by Companies, (K Units), 2018-2023
Table 6. Global Single Plane Illumination Microscopy Sales Share by Companies, 2018-2023
Table 7. Key Manufacturers Single Plane Illumination Microscopy Price (2018-2023) & (USD/Unit)
Table 8. Global Manufacturers Single Plane Illumination Microscopy Product Type
Table 9. List of Global Tier 1 Single Plane Illumination Microscopy Companies, Revenue (US$, Mn) in 2022 and Market Share
Table 10. List of Global Tier 2 and Tier 3 Single Plane Illumination Microscopy Companies, Revenue (US$, Mn) in 2022 and Market Share
Table 11. By Type – Global Single Plane Illumination Microscopy Revenue, (US$, Mn), 2022 & 2029
Table 12. By Type - Global Single Plane Illumination Microscopy Revenue (US$, Mn), 2018-2023
Table 13. By Type - Global Single Plane Illumination Microscopy Revenue (US$, Mn), 2024-2029
Table 14. By Type - Global Single Plane Illumination Microscopy Sales (K Units), 2018-2023
Table 15. By Type - Global Single Plane Illumination Microscopy Sales (K Units), 2024-2029
Table 16. By Application – Global Single Plane Illumination Microscopy Revenue, (US$, Mn), 2022 & 2029
Table 17. By Application - Global Single Plane Illumination Microscopy Revenue (US$, Mn), 2018-2023
Table 18. By Application - Global Single Plane Illumination Microscopy Revenue (US$, Mn), 2024-2029
Table 19. By Application - Global Single Plane Illumination Microscopy Sales (K Units), 2018-2023
Table 20. By Application - Global Single Plane Illumination Microscopy Sales (K Units), 2024-2029
Table 21. By Region – Global Single Plane Illumination Microscopy Revenue, (US$, Mn), 2022 VS 2029
Table 22. By Region - Global Single Plane Illumination Microscopy Revenue (US$, Mn), 2018-2023
Table 23. By Region - Global Single Plane Illumination Microscopy Revenue (US$, Mn), 2024-2029
Table 24. By Region - Global Single Plane Illumination Microscopy Sales (K Units), 2018-2023
Table 25. By Region - Global Single Plane Illumination Microscopy Sales (K Units), 2024-2029
Table 26. By Country - North America Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2023
Table 27. By Country - North America Single Plane Illumination Microscopy Revenue, (US$, Mn), 2024-2029
Table 28. By Country - North America Single Plane Illumination Microscopy Sales, (K Units), 2018-2023
Table 29. By Country - North America Single Plane Illumination Microscopy Sales, (K Units), 2024-2029
Table 30. By Country - Europe Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2023
Table 31. By Country - Europe Single Plane Illumination Microscopy Revenue, (US$, Mn), 2024-2029
Table 32. By Country - Europe Single Plane Illumination Microscopy Sales, (K Units), 2018-2023
Table 33. By Country - Europe Single Plane Illumination Microscopy Sales, (K Units), 2024-2029
Table 34. By Region - Asia Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2023
Table 35. By Region - Asia Single Plane Illumination Microscopy Revenue, (US$, Mn), 2024-2029
Table 36. By Region - Asia Single Plane Illumination Microscopy Sales, (K Units), 2018-2023
Table 37. By Region - Asia Single Plane Illumination Microscopy Sales, (K Units), 2024-2029
Table 38. By Country - South America Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2023
Table 39. By Country - South America Single Plane Illumination Microscopy Revenue, (US$, Mn), 2024-2029
Table 40. By Country - South America Single Plane Illumination Microscopy Sales, (K Units), 2018-2023
Table 41. By Country - South America Single Plane Illumination Microscopy Sales, (K Units), 2024-2029
Table 42. By Country - Middle East & Africa Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2023
Table 43. By Country - Middle East & Africa Single Plane Illumination Microscopy Revenue, (US$, Mn), 2024-2029
Table 44. By Country - Middle East & Africa Single Plane Illumination Microscopy Sales, (K Units), 2018-2023
Table 45. By Country - Middle East & Africa Single Plane Illumination Microscopy Sales, (K Units), 2024-2029
Table 46. Zesis Company Summary
Table 47. Zesis Single Plane Illumination Microscopy Product Offerings
Table 48. Zesis Single Plane Illumination Microscopy Sales (K Units), Revenue (US$, Mn) and Average Price (USD/Unit) (2018-2023)
Table 49. Zesis Key News & Latest Developments
Table 50. Miltenyi Biotec Company Summary
Table 51. Miltenyi Biotec Single Plane Illumination Microscopy Product Offerings
Table 52. Miltenyi Biotec Single Plane Illumination Microscopy Sales (K Units), Revenue (US$, Mn) and Average Price (USD/Unit) (2018-2023)
Table 53. Miltenyi Biotec Key News & Latest Developments
Table 54. Bruker Company Summary
Table 55. Bruker Single Plane Illumination Microscopy Product Offerings
Table 56. Bruker Single Plane Illumination Microscopy Sales (K Units), Revenue (US$, Mn) and Average Price (USD/Unit) (2018-2023)
Table 57. Bruker Key News & Latest Developments
Table 58. Leica Company Summary
Table 59. Leica Single Plane Illumination Microscopy Product Offerings
Table 60. Leica Single Plane Illumination Microscopy Sales (K Units), Revenue (US$, Mn) and Average Price (USD/Unit) (2018-2023)
Table 61. Leica Key News & Latest Developments
Table 62. Nuohai Company Summary
Table 63. Nuohai Single Plane Illumination Microscopy Product Offerings
Table 64. Nuohai Single Plane Illumination Microscopy Sales (K Units), Revenue (US$, Mn) and Average Price (USD/Unit) (2018-2023)
Table 65. Nuohai Key News & Latest Developments
Table 66. Single Plane Illumination Microscopy Production Capacity (K Units) of Key Manufacturers in Global Market, 2021-2023 (K Units)
Table 67. Global Single Plane Illumination Microscopy Capacity Market Share of Key Manufacturers, 2021-2023
Table 68. Global Single Plane Illumination Microscopy Production by Region, 2018-2023 (K Units)
Table 69. Global Single Plane Illumination Microscopy Production by Region, 2024-2029 (K Units)
Table 70. Single Plane Illumination Microscopy Market Opportunities & Trends in Global Market
Table 71. Single Plane Illumination Microscopy Market Drivers in Global Market
Table 72. Single Plane Illumination Microscopy Market Restraints in Global Market
Table 73. Single Plane Illumination Microscopy Raw Materials
Table 74. Single Plane Illumination Microscopy Raw Materials Suppliers in Global Market
Table 75. Typical Single Plane Illumination Microscopy Downstream
Table 76. Single Plane Illumination Microscopy Downstream Clients in Global Market
Table 77. Single Plane Illumination Microscopy Distributors and Sales Agents in Global Market
List of Figures
Figure 1. Single Plane Illumination Microscopy Segment by Type in 2022
Figure 2. Single Plane Illumination Microscopy Segment by Application in 2022
Figure 3. Global Single Plane Illumination Microscopy Market Overview: 2022
Figure 4. Key Caveats
Figure 5. Global Single Plane Illumination Microscopy Market Size: 2022 VS 2029 (US$, Mn)
Figure 6. Global Single Plane Illumination Microscopy Revenue, 2018-2029 (US$, Mn)
Figure 7. Single Plane Illumination Microscopy Sales in Global Market: 2018-2029 (K Units)
Figure 8. The Top 3 and 5 Players Market Share by Single Plane Illumination Microscopy Revenue in 2022
Figure 9. By Type - Global Single Plane Illumination Microscopy Revenue, (US$, Mn), 2022 & 2029
Figure 10. By Type - Global Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
Figure 11. By Type - Global Single Plane Illumination Microscopy Sales Market Share, 2018-2029
Figure 12. By Type - Global Single Plane Illumination Microscopy Price (USD/Unit), 2018-2029
Figure 13. By Application - Global Single Plane Illumination Microscopy Revenue, (US$, Mn), 2022 & 2029
Figure 14. By Application - Global Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
Figure 15. By Application - Global Single Plane Illumination Microscopy Sales Market Share, 2018-2029
Figure 16. By Application - Global Single Plane Illumination Microscopy Price (USD/Unit), 2018-2029
Figure 17. By Region - Global Single Plane Illumination Microscopy Revenue, (US$, Mn), 2022 & 2029
Figure 18. By Region - Global Single Plane Illumination Microscopy Revenue Market Share, 2018 VS 2022 VS 2029
Figure 19. By Region - Global Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
Figure 20. By Region - Global Single Plane Illumination Microscopy Sales Market Share, 2018-2029
Figure 21. By Country - North America Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
Figure 22. By Country - North America Single Plane Illumination Microscopy Sales Market Share, 2018-2029
Figure 23. US Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 24. Canada Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 25. Mexico Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 26. By Country - Europe Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
Figure 27. By Country - Europe Single Plane Illumination Microscopy Sales Market Share, 2018-2029
Figure 28. Germany Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 29. France Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 30. U.K. Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 31. Italy Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 32. Russia Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 33. Nordic Countries Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 34. Benelux Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 35. By Region - Asia Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
Figure 36. By Region - Asia Single Plane Illumination Microscopy Sales Market Share, 2018-2029
Figure 37. China Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 38. Japan Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 39. South Korea Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 40. Southeast Asia Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 41. India Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 42. By Country - South America Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
Figure 43. By Country - South America Single Plane Illumination Microscopy Sales Market Share, 2018-2029
Figure 44. Brazil Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 45. Argentina Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 46. By Country - Middle East & Africa Single Plane Illumination Microscopy Revenue Market Share, 2018-2029
Figure 47. By Country - Middle East & Africa Single Plane Illumination Microscopy Sales Market Share, 2018-2029
Figure 48. Turkey Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 49. Israel Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 50. Saudi Arabia Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 51. UAE Single Plane Illumination Microscopy Revenue, (US$, Mn), 2018-2029
Figure 52. Global Single Plane Illumination Microscopy Production Capacity (K Units), 2018-2029
Figure 53. The Percentage of Production Single Plane Illumination Microscopy by Region, 2022 VS 2029
Figure 54. Single Plane Illumination Microscopy Industry Value Chain
Figure 55. Marketing Channels
※参考情報 選択的平面照明顕微鏡(SPIM)は、特に生物学や発生学の研究において高解像度かつ迅速な三次元イメージングを可能にする先進的な顕微鏡技術です。SPIMはその名の通り、特定の平面を選択的に照明することに特化しており、これにより試料の深部を迅速かつ効果的に観察することができます。 SPIMの原理はシンプルでありながら、非常に強力です。従来の顕微鏡技術では、照明源が全体を均一に照らすため、深い位置にある構造物が焦点がぼやけることがあります。対照的に、SPIMは試料の特定の平面だけを照らすことによって、より鮮明で高解像度の画像を得ることができます。この方法では、各平面を連続的に照らしながらイメージングを行うため、三次元のデータを一度に取得することができ、顕微鏡の使用効率が大幅に向上します。 SPIMの特徴には、まずその非侵襲性があります。照明が試料の特定の平面に限定されているため、試料全体に光を当てる必要がなく、細胞や生物の構造を損傷せずに観察することができます。さらに、SPIMは照明が薄いため、試料の蛍光信号のブリーチングが少なく、長時間の観察が可能です。この特長により、細胞の動きや発生過程をリアルタイムで追跡することができます。 SPIMにはいくつかの種類があります。最も一般的なものは、ラジアル対称の光源を用いたシステムで、これにより照明面を自由に調整することができます。さらに、SPIMはエンジンとしての光源から2次元の光束を発生させることで、試料表面に選択的に光をあてることができる設計も存在します。また、多方向から照明を行うマルチスリットSPIMのようなバリエーションもあり、これによりより一層の高解像度と信号強度の向上が可能となります。 SPIMの用途は多岐にわたります。生物学の分野においては、細胞の発生過程や分裂過程の観察、神経細胞の接続の研究、さらには発生中の胚の成長過程のイメージングなどに利用されています。また、SPIMは生体サンプルの観察にも特に適しており、蛍光プローブを使用することで、特定の細胞成分の特定や追跡が可能です。医療分野でも、SPIMを用いることで、癌細胞の研究や治療法の開発にも貢献しています。 さらに、SPIMは多次元イメージングが可能であるため、データの取得後にはさまざまな後処理が行われ、三次元モデルを生成することができます。これにより、研究者は試料の詳細なモデルを作成し、各部位の機能や相互作用を深く理解するためのツールとして利用することができます。このような利用は特に発生生物学、病理学、組織学などの分野で重要視されています。 SPIMに関連する技術には、蛍光顕微鏡技術、光学トムグラフィー、デジタルスライスイメージングなどがあります。蛍光顕微鏡技術は、SPIMとは異なり全体照明で画像を取得しますが、SPIMと組み合わせることで、より優れた分解能を得ることができます。また、光学トムグラフィーは、光学的に厚みのある試料の内部構造を三次元的に再構成する技術であり、SPIMと統合することで、複雑な試料の詳細な解析が可能になります。 今後の展望として、SPIM技術はさらなる進化が期待されており、例えば高速撮影技術や多様な照明オプションの開発が進んでいます。これにより、より詳細なリアルタイムイメージングが可能となり、さまざまな生物学的プロセスを解明する新たな道を拓くでしょう。SPIMは、生命科学の発展に大きな影響を与え続けており、その利用可能性は今後ますます広がると考えられています。 このように、選択的平面照明顕微鏡(SPIM)は、生物学的研究における強力なツールとして、多くの可能性を秘めています。非常に鮮明な三次元画像を提供し、細胞や生物の動きを非侵襲的に観察できるその能力は、生命科学における新しい発見や治療法の開発において重要な役割を果たしています。未来に向けた技術の進展により、SPIMはますます多くの研究分野で活用されることでしょう。 |
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