1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Technology Analysis
3.8 Application Analysis
3.9 End User Analysis
3.10 Emerging Markets
3.11 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global In-vitro Toxicology Testing Market, By Product Type
5.1 Introduction
5.2 Software
5.3 Assay Kits
5.3.1 Enzyme Toxicity Assays
5.3.2 Receptor-Binding Assays
5.3.3 Tissue Culture Assays
5.3.4 Bacterial Toxicity Assays
5.3.5 Enzyme Toxicity Assays
5.3.6 Cell-based Elisa & Western Blots
5.4 Equipment
5.5 Consumables
5.6 Other Product Types
6 Global In-vitro Toxicology Testing Market, By Method
6.1 Introduction
6.2 Cellular Assay
6.2.1 High Throughput / High Content Screening
6.2.2 Molecular Imaging
6.2.3 Live Cells
6.2.4 Confocal Microscopy
6.2.5 Fixed Cells
6.3 In Silica
6.4 Biochemical Assay
7 Global In-vitro Toxicology Testing Market, By Technology
7.1 Introduction
7.2 Molecular Imaging
7.3 High Throughput Technology
7.4 Cell Culture Technology
7.5 OMICS Technology
7.6 Other Technologies
8 Global In-vitro Toxicology Testing Market, By Toxicity Endpoint & Test
8.1 Introduction
8.2 Genotoxicity
8.3 Cytotoxicity
8.4 Organ Toxicity
8.5 Phototoxicity
8.6 Dermal Toxicity
8.7 Kin irritation, Corrosion, & Sensitization
8.8 Absorption, Distribution, Metabolism, & Excretion
8.9 Other Toxicity Endpoint & Tests
9 Global In-vitro Toxicology Testing Market, By Application
9.1 Introduction
9.2 Endocrine Disruption
9.3 Systemic Toxicology
9.4 Occular Toxicity
9.5 Other Applications
10 Global In-vitro Toxicology Testing Market, By End User
10.1 Introduction
10.2 Pharmaceuticals Industry
10.3 Cosmetics and Households Products
10.4 Food Industry
10.5 Chemicals Industry
10.6 Diagnostics
10.7 Academic Institutes & Research Laboratories
10.8 Other End Users
11 Global In-vitro Toxicology Testing Market, By Geography
11.1 Introduction
11.2 North America
11.2.1 US
11.2.2 Canada
11.2.3 Mexico
11.3 Europe
11.3.1 Germany
11.3.2 UK
11.3.3 Italy
11.3.4 France
11.3.5 Spain
11.3.6 Rest of Europe
11.4 Asia Pacific
11.4.1 Japan
11.4.2 China
11.4.3 India
11.4.4 Australia
11.4.5 New Zealand
11.4.6 South Korea
11.4.7 Rest of Asia Pacific
11.5 South America
11.5.1 Argentina
11.5.2 Brazil
11.5.3 Chile
11.5.4 Rest of South America
11.6 Middle East & Africa
11.6.1 Saudi Arabia
11.6.2 UAE
11.6.3 Qatar
11.6.4 South Africa
11.6.5 Rest of Middle East & Africa
12 Key Developments
12.1 Agreements, Partnerships, Collaborations and Joint Ventures
12.2 Acquisitions & Mergers
12.3 New Product Launch
12.4 Expansions
12.5 Other Key Strategies
13 Company Profiling
13.1 Agilent Technologies
13.2 Abbott Laboratories
13.3 Covance
13.4 Bio-Rad Laboratories
13.5 GE Healthcare
13.6 Promega Corporation
13.7 Quest Diagnostics
13.8 Thermo Fisher Scientific
13.9 Merck KGaA
13.10 Eurofins Scientific
13.11 Evotec
13.12 Gentronix
13.13 BioIVT
13.14 Agilent Technologies
13.15 Catalent, Inc.
13.16 Thermo Fisher Scientific Inc.
13.17 Charles River
13.18 Helsinn Holding S.A.
13.19 Laboratory Corporation of America Holdings
13.20 Heron Therapeutics Inc,
List of Tables
Table 1 Global In-vitro Toxicology Testing Market Outlook, By Region (2021-2030) ($MN)
Table 2 Global In-vitro Toxicology Testing Market Outlook, By Product Type (2021-2030) ($MN)
Table 3 Global In-vitro Toxicology Testing Market Outlook, By Software (2021-2030) ($MN)
Table 4 Global In-vitro Toxicology Testing Market Outlook, By Assay Kits (2021-2030) ($MN)
Table 5 Global In-vitro Toxicology Testing Market Outlook, By Enzyme Toxicity Assays (2021-2030) ($MN)
Table 6 Global In-vitro Toxicology Testing Market Outlook, By Receptor-Binding Assays (2021-2030) ($MN)
Table 7 Global In-vitro Toxicology Testing Market Outlook, By Tissue Culture Assays (2021-2030) ($MN)
Table 8 Global In-vitro Toxicology Testing Market Outlook, By Bacterial Toxicity Assays (2021-2030) ($MN)
Table 9 Global In-vitro Toxicology Testing Market Outlook, By Enzyme Toxicity Assays (2021-2030) ($MN)
Table 10 Global In-vitro Toxicology Testing Market Outlook, By Cell-based Elisa & Western Blots (2021-2030) ($MN)
Table 11 Global In-vitro Toxicology Testing Market Outlook, By Equipment (2021-2030) ($MN)
Table 12 Global In-vitro Toxicology Testing Market Outlook, By Consumables (2021-2030) ($MN)
Table 13 Global In-vitro Toxicology Testing Market Outlook, By Other Product Types (2021-2030) ($MN)
Table 14 Global In-vitro Toxicology Testing Market Outlook, By Method (2021-2030) ($MN)
Table 15 Global In-vitro Toxicology Testing Market Outlook, By Cellular Assay (2021-2030) ($MN)
Table 16 Global In-vitro Toxicology Testing Market Outlook, By High Throughput / High Content Screening (2021-2030) ($MN)
Table 17 Global In-vitro Toxicology Testing Market Outlook, By Molecular Imaging (2021-2030) ($MN)
Table 18 Global In-vitro Toxicology Testing Market Outlook, By Live Cells (2021-2030) ($MN)
Table 19 Global In-vitro Toxicology Testing Market Outlook, By Confocal Microscopy (2021-2030) ($MN)
Table 20 Global In-vitro Toxicology Testing Market Outlook, By Fixed Cells (2021-2030) ($MN)
Table 21 Global In-vitro Toxicology Testing Market Outlook, By In Silica (2021-2030) ($MN)
Table 22 Global In-vitro Toxicology Testing Market Outlook, By Biochemical Assay (2021-2030) ($MN)
Table 23 Global In-vitro Toxicology Testing Market Outlook, By Technology (2021-2030) ($MN)
Table 24 Global In-vitro Toxicology Testing Market Outlook, By Molecular Imaging (2021-2030) ($MN)
Table 25 Global In-vitro Toxicology Testing Market Outlook, By High Throughput Technology (2021-2030) ($MN)
Table 26 Global In-vitro Toxicology Testing Market Outlook, By Cell Culture Technology (2021-2030) ($MN)
Table 27 Global In-vitro Toxicology Testing Market Outlook, By OMICS Technology (2021-2030) ($MN)
Table 28 Global In-vitro Toxicology Testing Market Outlook, By Other Technologies (2021-2030) ($MN)
Table 29 Global In-vitro Toxicology Testing Market Outlook, By Toxicity Endpoint & Test (2021-2030) ($MN)
Table 30 Global In-vitro Toxicology Testing Market Outlook, By Genotoxicity (2021-2030) ($MN)
Table 31 Global In-vitro Toxicology Testing Market Outlook, By Cytotoxicity (2021-2030) ($MN)
Table 32 Global In-vitro Toxicology Testing Market Outlook, By Organ Toxicity (2021-2030) ($MN)
Table 33 Global In-vitro Toxicology Testing Market Outlook, By Phototoxicity (2021-2030) ($MN)
Table 34 Global In-vitro Toxicology Testing Market Outlook, By Dermal Toxicity (2021-2030) ($MN)
Table 35 Global In-vitro Toxicology Testing Market Outlook, By Kin irritation, Corrosion, & Sensitization (2021-2030) ($MN)
Table 36 Global In-vitro Toxicology Testing Market Outlook, By Absorption, Distribution, Metabolism, & Excretion (2021-2030) ($MN)
Table 37 Global In-vitro Toxicology Testing Market Outlook, By Other Toxicity Endpoint & Tests (2021-2030) ($MN)
Table 38 Global In-vitro Toxicology Testing Market Outlook, By Application (2021-2030) ($MN)
Table 39 Global In-vitro Toxicology Testing Market Outlook, By Endocrine Disruption (2021-2030) ($MN)
Table 40 Global In-vitro Toxicology Testing Market Outlook, By Systemic Toxicology (2021-2030) ($MN)
Table 41 Global In-vitro Toxicology Testing Market Outlook, By Occular Toxicity (2021-2030) ($MN)
Table 42 Global In-vitro Toxicology Testing Market Outlook, By Other Applications (2021-2030) ($MN)
Table 43 Global In-vitro Toxicology Testing Market Outlook, By End User (2021-2030) ($MN)
Table 44 Global In-vitro Toxicology Testing Market Outlook, By Pharmaceuticals Industry (2021-2030) ($MN)
Table 45 Global In-vitro Toxicology Testing Market Outlook, By Cosmetics and Households Products (2021-2030) ($MN)
Table 46 Global In-vitro Toxicology Testing Market Outlook, By Food Industry (2021-2030) ($MN)
Table 47 Global In-vitro Toxicology Testing Market Outlook, By Chemicals Industry (2021-2030) ($MN)
Table 48 Global In-vitro Toxicology Testing Market Outlook, By Diagnostics (2021-2030) ($MN)
Table 49 Global In-vitro Toxicology Testing Market Outlook, By Academic Institutes & Research Laboratories (2021-2030) ($MN)
Table 50 Global In-vitro Toxicology Testing Market Outlook, By Other End Users (2021-2030) ($MN)
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.
| ※参考情報 体外毒性試験（In-vitro Toxicology Testing）は、生体外で化学物質や化合物の毒性を評価する手法です。これは、動物実験に代わる方法として注目されており、倫理的問題を軽減し、より早くかつ安価に毒性評価を行うことができます。この試験は、医薬品、化粧品、農薬、工業化学品など、さまざまな分野で広く利用されています。 体外毒性試験の種類には、様々なアプローチがあります。まず、細胞培養を用いた試験が一般的であり、特定の細胞株を用いて試験物質の影響を観察します。細胞障害性試験では、細胞の生存率や繁殖能力を測定し、毒性の程度を評価します。また、遺伝毒性試験では、試験物質がDNA損傷や突然変異を引き起こすかどうかを検査します。 次に、特定の生理学的な反応を評価するための試験も存在します。例えば、腫瘍形成試験では、発がん性のリスクを評価するために、細胞が無秩序に増殖するかどうかを観察します。さらに、代謝毒性試験では、肝臓などの代謝器官の機能や、物質が代謝された際に生成される中間産物の毒性を評価します。 体外毒性試験の用途は多岐にわたります。医薬品開発においては、新薬候補の毒性を早期に評価することで、安全性の高い薬剤を選別する助けになります。化粧品業界でも、製品の安全性を保証するために体外毒性試験が活用されています。また、環境評価においては、新しい化学物質が生態系に与える影響を事前に評価する手段として利用されます。 関連技術としては、オミクス技術や人工知能（AI）を駆使した解析手法が進化しています。ゲノム、プロテオーム、メタボロームなどを解析することで、より詳細な生物学的反応を理解し、毒性機構を解明することが可能です。AIは、大量のデータを迅速に分析し、毒性予測モデルを構築するのに役立ちます。これにより、試験の精度と効率が向上しています。 さらに、オルガノイド技術なども注目されています。オルガノイドは、特定の器官を模倣した3次元の細胞塊であり、より生理的な環境での毒性評価が可能です。これにより、従来の2次元細胞培養よりも実際の生体反応に近い結果を得ることができます。 体外毒性試験は、動物モデルの代替を目指し、多くの国で規制当局が推進しています。これにより、持続可能な開発や社会的責任の視点からも重要な役割を果たしています。今後も、科学技術の進展によって新たな評価方法が開発され、より信頼性の高い毒性試験が可能になることが期待されます。 総じて、体外毒性試験は、化学物質の安全性評価において重要な手段であり、今後の医療や環境保護においてもその重要性は増していくでしょう。技術の進歩にあたっては、安全性と倫理のバランスを考慮しながら、持続可能な未来を目指すことが求められます。 |
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