米国の整形外科用バイオマテリアル市場

iData Researchが発行した調査報告書(iDATA_USOB15_RPT)
◆英語タイトル:U.S. Orthopedic Biomaterials Market
◆商品コード:iDATA_USOB15_RPT
◆発行会社(リサーチ会社):iData Research
◆発行日:2015年1月
◆ページ数:288
◆レポート形式:英語 / pdf
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◆調査対象地域:米国
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【レポートの概要】

The U.S. orthopedic biomaterials market includes bone graft substitutes, growth factors, orthopedic stem cells, cell therapy, hyaluronic acid viscosupplementation, cartilage repair and machined bone allografts.

Report Contents
Competitor Analysis
Identified Strategic Opportunities
Indepth Procedure Volumes
Market Overview by Segment
Trend Analysis by Segment
Market Drivers & Limiters
Mergers & Acquisitions
Customer Feedback and Market Monitoring

Main Segments Covered
U.S. Orthopedic Biomaterials Procedures
Orthopedic Bone Graft Substitute Market
Orthopedic Growth Factor Market
Orthopedic Stem Cell Market
Orthopedic Cell Therapy Market
Orthopedic Hyaluronic Acid Viscosupplementation Market
Orthopedic Cartilage Repair Market
pinal Machined Bone Allograft Market

【レポートの目次】

TABLE OF CONTENTS
TABLE OF CONTENTS I
LIST OF FIGURES XI
LIST OF CHARTS XVII
EXECUTIVE SUMMARY 1
1.1 U.S. MARKET FOR ORTHOPEDIC BIOMATERIALS 1
1.2 ORTHOPEDIC BONE GRAFT SUBSTITUTE MARKET 2
1.3 ORTHOPEDIC GROWTH FACTOR MARKET 3
1.4 ORTHOPEDIC STEM CELL MARKET 4
1.5 ORTHOPEDIC CELL THERAPY MARKET 5
1.6 ORTHOPEDIC HYALURONIC ACID VISCOSUPPLEMENTATION MARKET 6
1.7 ORTHOPEDIC CARTILAGE REPAIR MARKET 7
1.8 SPINAL MACHINED BONE ALLOGRAFT MARKET 8
1.9 LEADING COMPETITORS 9
RESEARCH METHODOLOGY 11
2.1 RESEARCH SCOPE 11
2.2 IDATA’S 9-STEP METHODOLOGY 11
Step 1: Project Initiation & Team Selection 11
Step 2: Prepare Data Systems and Perform Secondary Research 13
Step 3: Preparation for Interviews & Questionnaire Design 14
Step 4: Performing Primary Research 15
Step 5: Research Analysis: Establishing Baseline Estimates 17
Step 6: Market Forecast and Analysis 18
Step 7: Identify Strategic Opportunities 20
Step 8: Final Review and Market Release 21
Step 9: Customer Feedback and Market Monitoring 22
U.S. ORTHOPEDIC BIOMATERIALS MARKET OVERVIEW 23
3.1 INTRODUCTION 23
3.1.1 Bone Graft Substitutes 24
3.1.2 Growth Factors 24
3.1.3 Orthopedic Stem Cell Therapy 25
3.1.4 Cell Therapies 25
3.1.5 Hyaluronic Acid Viscosupplementation 25
3.1.6 Cartilage Repair 26
3.1.7 Spinal Machined Bone Allografts 26
3.2 MARKET OVERVIEW 27
3.3 TREND ANALYSIS BY SEGMENT 32
3.4 DRIVERS AND LIMITERS 35
3.4.1 Market Drivers 35
3.4.2 Market Limiters 36
3.5 COMPETITIVE ANALYSIS 38
3.6 HERFINDAHL INDEX 46
3.7 MERGERS AND ACQUISITIONS 48
PROCEDURE NUMBERS 53
4.1 PROCEDURAL DEFINITIONS 53
4.2 BONE GRAFT PROCEDURE NUMBERS BY TYPE 54
4.3 BONE GRAFT SUBSTITUTE PROCEDURE NUMBERS 57
4.3.1 By Material 57
4.3.2 By Indication 59
4.4 GROWTH FACTOR BONE GRAFT PROCEDURE NUMBERS 61
4.5 STEM CELL BONE GRAFT PROCEDURE NUMBERS 63
4.6 CELL THERAPY TREATMENT NUMBERS 65
4.6.1 Overview by Type 65
4.6.2 Platelet-Rich Plasma Treatment Numbers by Indication 67
4.6.3 Bone Marrow Concentrate Treatment Numbers by Indication 68
4.7 HYALURONIC ACID TREATMENT NUMBERS BY TYPE 69
4.8 CARTILAGE REPAIR PROCEDURE NUMBERS BY TYPE 71
4.9 SPINAL MACHINED BONE ALLOGRAFT PROCEDURE NUMBERS BY APPROACH 74
ORTHOPEDIC BONE GRAFT SUBSTITUTE MARKET 77
5.1 INTRODUCTION 77
5.2 MARKET SEGMENTATION 78
5.2.1 By Indication 78
5.2.1.1 Spine 78
5.2.1.2 Trauma 79
5.2.1.3 Large Joint 79
5.2.1.4 Foot Reconstruction 79
5.2.1.5 Craniomaxillofacial 79
5.2.1.6 Oncology 79
5.2.2 By Material 79
5.2.2.1 Autograft 79
5.2.2.2 Standard Allograft 79
5.2.2.3 Demineralized Bone Matrix 80
5.2.2.4 Synthetic 80
5.2.2.5 Xenograft 80
5.3 PROCEDURE NUMBERS 81
5.3.1 Bone Graft Substitutes Procedure Numbers by Material 81
5.3.2 Units Per Procedure by Indication 83
5.4 MARKET OVERVIEW 84
5.4.1 Bone Graft Substitute Market by Material 84
5.4.2 Bone Graft Substitute Market by Indication 88
5.5 MARKET ANALYSIS AND FORECAST 92
5.5.1 Total Orthopedic Bone Graft Substitute Market 92
5.5.2 Bone Graft Substitute Market by Material 94
5.5.2.1 Total Allograft Bone Graft Substitute Market 94
5.5.2.2 Allograft Bone Graft Substitute Market by Indication 96
5.5.2.2.1 Spine 97
5.5.2.2.1.1 Cervical Spine 98
5.5.2.2.1.2 Thoracolumbar Spine 99
5.5.2.2.2 Trauma 100
5.5.2.2.2.1 Non-union Trauma 101
5.5.2.2.2.2 Fresh Fracture Trauma 102
5.5.2.2.3 Large Joint Reconstruction 103
5.5.2.2.3.1 Hip Large Joint Reconstruction 104
5.5.2.2.3.2 Knee Large Joint Reconstruction 105
5.5.2.2.4 Foot Reconstruction 106
5.5.2.2.5 Craniomaxillofacial 107
5.5.2.2.6 Oncology 108
5.5.2.3 Total Demineralized Bone Matrix Market 109
5.5.2.4 Demineralized Bone Matrix Market, with and without Carriers 111
5.5.2.5 Demineralized Bone Matrix Market by Indication 112
5.5.2.5.1 Spine 113
5.5.2.5.1.1 Cervical Spine 114
5.5.2.5.1.2 Thoracolumbar Spine 115
5.5.2.5.2 Trauma 116
5.5.2.5.2.1 Non-union Trauma 117
5.5.2.5.2.2 Fresh Fracture Trauma 118
5.5.2.5.3 Large Joint Reconstruction 119
5.5.2.5.3.1 Hip Large Joint Reconstruction 120
5.5.2.5.3.2 Knee Large Joint Reconstruction 121
5.5.2.5.4 Foot Reconstruction 122
5.5.2.5.5 Craniomaxillofacial 123
5.5.2.5.6 Oncology 124
5.5.2.6 Total Synthetic Bone Graft Substitute Market 125
5.5.2.7 Synthetic Bone Graft Substitute Market by Indication 127
5.5.2.7.1 Spine 128
5.5.2.7.1.1 Cervical Spine 129
5.5.2.7.1.2 Thoracolumbar Spine 130
5.5.2.7.2 Trauma 131
5.5.2.7.2.1 Non-union Trauma 132
5.5.2.7.2.2 Fresh Fracture Trauma 133
5.5.2.7.3 Large Joint Reconstruction 134
5.5.2.7.3.1 Hip Large Joint Reconstruction 135
5.5.2.7.3.2 Knee Large Joint Reconstruction 136
5.5.2.7.4 Foot Reconstruction 137
5.5.2.7.5 Craniomaxillofacial 138
5.5.2.7.6 Oncology 139
5.5.3 Bone Graft Substitute Market by Indication 140
5.5.3.1 Spine Bone Graft Substitute Market 140
5.5.3.1.1 Cervical Spine Bone Graft Substitute Market 142
5.5.3.1.2 Thoracolumbar Spine Bone Graft Substitute Market 144
5.5.3.2 Trauma Bone Graft Substitute Market 146
5.5.3.2.1 Non-union Trauma Fracture Bone Graft Substitute Market 148
5.5.3.2.2 Fresh Fracture Trauma Bone Graft Substitute Market 149
5.5.3.3 Large Joint Reconstruction Bone Graft Substitute Market 150
5.5.3.3.1 Hip Large Joint Reconstruction Bone Graft Substitute Market 152
5.5.3.3.2 Knee Large Joint Reconstruction Bone Graft Substitute Market 153
5.5.3.4 Foot Reconstruction Bone Graft Substitute Market 154
5.5.3.5 Craniomaxillofacial Bone Graft Substitute Market 156
5.5.3.6 Oncology Bone Graft Substitute Market 158
5.6 DRIVERS AND LIMITERS 160
5.6.1 Market Drivers 160
5.6.1.1 Allograft Bone Graft Substitute Market 160
5.6.1.2 Demineralized Bone Matrix Bone Graft Substitute Market 160
5.6.1.3 Synthetic Bone Graft Substitute Market 161
5.6.2 Market Limiters 163
5.6.2.1 Allograft Bone Graft Substitute Market 163
5.6.2.2 Demineralized Bone Matrix Bone Graft Substitute Market 163
5.6.2.3 Synthetic Bone Graft Substitute Market 163
5.7 COMPETITIVE ANALYSIS 165
ORTHOPEDIC GROWTH FACTOR MARKET 173
6.1 INTRODUCTION 173
6.1.1 BMP-2 (Medtronic) 174
6.1.2 BMP-7 (Olympus Biomaterials) 174
6.2 MARKET ANALYSIS AND FORECAST 175
6.3 DRIVERS AND LIMITERS 177
6.3.1 Market Drivers 177
6.3.2 Market Limiters 177
6.4 COMPETITIVE ANALYSIS 180
ORTHOPEDIC STEM CELL MARKET 183
7.1 INTRODUCTION 183
7.1.1 Lineage 183
7.1.1.1 Human Embryonic Stem Cells (hESC) 183
7.1.1.2 Mesenchymal Stem Cells (MSC) 184
7.1.2 Other Therapeutic Applications 184
7.2 MARKET OVERVIEW 185
7.2.1 Orthopedic Stem Cell Market by Anatomy 185
7.3 MARKET ANALYSIS AND FORECAST 187
7.3.1 Total Orthopedic Stem Cell Market 187
7.3.2 Cervical Spine Stem Cell Market 189
7.3.3 Lumbar Spine Stem Cell Market 190
7.4 DRIVERS AND LIMITERS 191
7.4.1 Market Drivers 191
7.4.2 Market Limiters 192
7.5 COMPETITIVE ANALYSIS 194
ORTHOPEDIC CELL THERAPY MARKET 197
8.1 INTRODUCTION 197
8.1.1 Platelet-Rich Plasma 198
8.1.2 Concentrated Bone Marrow Aspirate 199
8.2 MARKET OVERVIEW 200
8.3 MARKET ANALYSIS AND FORECAST 203
8.3.1 Total Platelet-Rich Plasma Market 203
8.3.1.1 Soft Tissue Platelet-Rich Plasma Market 205
8.3.1.2 Orthopedic Platelet-Rich Plasma Market 206
8.3.1.3 Cardiac Platelet-Rich Plasma Market 207
8.3.1.4 Spine Platelet-Rich Plasma Market 208
8.3.1.5 Plastics Platelet-Rich Plasma Market 209
8.3.2 Total Bone Marrow Concentrate Market 210
8.3.2.1 Spine Bone Marrow Concentrate Market 212
8.3.2.2 Trauma Bone Marrow Concentrate Market 213
8.3.2.3 Soft Tissue Concentrated Bone Marrow Aspirate Market 214
8.3.2.4 Joint Reconstruction Bone Marrow Concentrate Market 215
8.4 DRIVERS AND LIMITERS 216
8.4.1 Market Drivers 216
8.4.2 Market Limiters 217
8.5 COMPETITIVE ANALYSIS 218
ORTHOPEDIC HYALURONIC ACID VISCOSUPPLEMENTATION MARKET 221
9.1 INTRODUCTION 221
9.1.1 Benefits of Viscosupplementation 222
9.1.2 Synovial Fluid 222
9.1.3 Product Types 223
9.1.3.1 Single-Injection Products 223
9.1.3.2 Three-Injection Cycle Products 223
9.1.3.3 Three/Five-Injection Cycle Products 223
9.1.4 Reimbursement 224
9.2 MARKET OVERVIEW 225
9.3 MARKET ANALYSIS AND FORECAST 229
9.3.1 Total Hyaluronic Acid Viscosupplementation Market 229
9.3.2 Single-Injection Hyaluronic Acid Viscosupplementation Market 231
9.3.3 Three-Injection Hyaluronic Acid Viscosupplementation Market 233
9.3.4 Five-Injection Hyaluronic Acid Viscosupplementation Market 235
9.4 DRIVERS AND LIMITERS 237
9.4.1 Market Drivers 237
9.4.2 Market Limiters 238
9.5 COMPETITIVE ANALYSIS 240
ORTHOPEDIC CARTILAGE REPAIR MARKET 243
10.1 INTRODUCTION 243
10.1.1 Anatomy 243
10.1.2 Methods for Cartilage Repair 243
10.1.2.1 Microfracture 243
10.1.2.2 Microfracture Adjunct 244
10.1.2.3 Osteoarticular Autograft Transfer System 244
10.1.2.4 Particulated Juvenile Allograft 244
10.1.2.5 Osteochondral Allograft Transfer 244
10.1.2.6 Autologous Chondrocyte Implantation 244
10.1.2.7 Meniscal Allograft Transplantation 245
10.2 MARKET OVERVIEW 245
10.3 MARKET ANALYSIS AND FORECAST 249
10.3.1 Osteochondral Allograft Market 249
10.3.2 Meniscal Allograft Market 251
10.3.3 Autologous Chondrocyte Implantation Market 253
10.3.4 Particulated Juvenile Allograft Implant Market 255
10.3.5 Microfracture Adjunct Market 257
10.4 DRIVERS AND LIMITERS 259
10.4.1 Market Drivers 259
10.4.2 Market Limiters 259
10.5 COMPETITIVE ANALYSIS 261
SPINAL MACHINED BONE ALLOGRAFT MARKET 265
11.1 INTRODUCTION 265
11.1.1 Anterior Lumbar Interbody Fusion (ALIF) 266
11.1.2 Posterior Lumbar Interbody Fusion (PLIF) 266
11.1.3 Transforaminal Lumbar Interbody Fusion (TLIF) 266
11.1.4 Lateral Lumbar Interbody Fusion (LLIF) 266
11.1.5 Cervical Interbody Fusion (CIF) 267
11.1.6 Machined Bone Material 267
11.2 MARKET OVERVIEW 268
11.3 MARKET ANALYSIS AND FORECAST 271
11.3.1 Total Spinal Machined Bone Allograft Market 271
11.3.2 ALIF Machined Bone Allograft Market 274
11.3.2.1 PLIF Machined Bone Allograft Market 276
11.3.2.2 TLIF Machined Bone Allograft Market 278
11.3.2.3 CIF Machined Bone Allograft Market 280
11.4 DRIVERS AND LIMITERS 282
11.4.1 Market Drivers 282
11.4.2 Market Limiters 283
11.5 COMPETITIVE ANALYSIS 286
ABBREVIATIONS 289

LIST OF CHARTS
Chart 1 1: Orthopedic Biomaterials Market, U.S., 2011 – 2021 1
Chart 1 2: Orthopedic Bone Graft Substitute Market Growth by Segment, U.S., 2014, 2017 and 2021 2
Chart 1 3: Orthopedic Growth Factor Market, U.S., 2011, 2014, 2017 and 2021 3
Chart 1 4: Orthopedic Stem Cell Market by Segment, U.S., 2014 and 2021 4
Chart 1 5: Orthopedic Cell Therapy Market by Segment, U.S., 2011 – 2021 5
Chart 1 6: Orthopedic Hyaluronic Acid Viscosupplementation Market Breakdown by Segment, U.S., 2011, 2014, 2017 and 2021 6
Chart 1 7: Orthopedic Cartilage Repair Market by Segment, U.S., 2014 7
Chart 1 8: Spinal Machined Bone Allograft Market by Segment, U.S., 2013 – 2015 8
Chart 1 9: Leading Competitors, Orthopedic Biomaterials Market U.S., 2014 9
Chart 3 1: Orthopedic Biomaterials Market by Segment, U.S., 2011 – 2021 30
Chart 3 2: Orthopedic Biomaterials Market Breakdown, U.S., 2014 31
Chart 3 3: Orthopedic Biomaterials Market Breakdown, U.S., 2021 31
Chart 3 4: Orthopedic Biomaterials Market Growth by Segment, U.S., 2011 – 2021 34
Chart 3 5: Leading Competitors, Orthopedic Biomaterials Market, U.S., 2014 45
Chart 3 6: Herfindahl Index, Orthopedic Biomaterials Market, U.S., 2014 47
Chart 4 1: Bone Graft Procedure Numbers By Type, U.S., 2011 – 2021 56
Chart 4 2: Bone Graft Substitute Procedure Numbers by Material, U.S., 2011 – 2021 58
Chart 4 3: Bone Graft Substitute Procedure Numbers by Indication, U.S., 2011 – 2021 60
Chart 4 4: Growth Factor Bone Graft Procedure Numbers, U.S., 2011 – 2021 62
Chart 4 5: Stem Cell Bone Graft Procedure Numbers, U.S., 2011 – 2021 64
Chart 4 6: Cell Therapy Treatment Numbers by Type, U.S., 2011 – 2021 66
Chart 4 7: Platelet-Rich Plasma Treatment Numbers By Indication, U.S., 2011 – 2021 67
Chart 4 8: Bone Marrow Concentrate Treatment Numbers By Indication, U.S., 2011 – 2021 68
Chart 4 9: Hyaluronic Acid Treatment Numbers By Type, U.S., 2011 – 2021 70
Chart 4 10: Cartilage Repair Procedure Numbers By Type, U.S., 2011 – 2021 73
Chart 4 11: Spinal Machined Bone Allograft Procedure Numbers by Approach, U.S., 2011 – 2021 75
Chart 5 1: Bone Graft Substitute Procedure Numbers By Material, U.S., 2011 – 2021 82
Chart 5 2: Orthopedic Bone Graft Substitute Market by Material, U.S., 2011 – 2021 86
Chart 5 3: Orthopedic Bone Graft Substitute Market Breakdown by Material, U.S., 2014 87
Chart 5 4: Orthopedic Bone Graft Substitute Market Breakdown by Material, U.S., 2021 87
Chart 5 5: Orthopedic Bone Graft Substitute Market by Indication, U.S., 2011 – 2021 90
Chart 5 6: Orthopedic Bone Graft Substitute Market Breakdown by Indication, U.S., 2014 91
Chart 5 7: Orthopedic Bone Graft Substitute Market Breakdown by Indication, U.S., 2021 91
Chart 5 8: Total Orthopedic Bone Graft Substitute Market, U.S., 2011 – 2021 93
Chart 5 9: Total Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 95
Chart 5 10: Allograft Bone Graft Substitute Market by Indication, U.S., 2011 – 2021 96
Chart 5 11: Total Spine Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 97
Chart 5 12: Cervical Spine Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 98
Chart 5 13: Thoracolumbar Spine Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 99
Chart 5 14: Total Trauma Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 100
Chart 5 15: Non-union Trauma Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 101
Chart 5 16: Fresh Fracture Trauma Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 102
Chart 5 17: Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 103
Chart 5 18: Hip Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S.,
2011 – 2021 104
Chart 5 19: Knee Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S.,
2011 – 2021 105
Chart 5 20: Foot Reconstruction Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 106
Chart 5 21: Craniomaxillofacial Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 107
Chart 5 22: Oncology Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 108
Chart 5 23: Total Demineralized Bone Matrix Market, U.S., 2011 – 2021 110
Chart 5 24: Demineralized Bone Matrix Market by Indication, U.S., 2011 – 2021 112
Chart 5 25: Spine Demineralized Bone Matrix Market, U.S., 2011 – 2021 113
Chart 5 26: Cervical Spine Demineralized Bone Matrix Market, U.S., 2011 – 2021 114
Chart 5 27: Thoracolumbar Spine Demineralized Bone Matrix Market, U.S., 2011 – 2021 115
Chart 5 28: Trauma Demineralized Bone Matrix Market, U.S., 2011 – 2021 116
Chart 5 29: Non-union Trauma Demineralized Bone Matrix Market, U.S., 2011 – 2021 117
Chart 5 30: Fresh Fracture Trauma Demineralized Bone Matrix Market, U.S., 2011 – 2021 118
Chart 5 31: Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2011 – 2021 119
Chart 5 32: Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2011 – 2021 120
Chart 5 33: Knee Large Joint Reconstruction Demineralized Bone Matrix Market, U.S.,
2011 – 2021 121
Chart 5 34: Foot Reconstruction Demineralized Bone Matrix Market, U.S., 2011 – 2021 122
Chart 5 35: Craniomaxillofacial Demineralized Bone Matrix Market, U.S., 2011 – 2021 123
Chart 5 36: Oncology Demineralized Bone Matrix Market, U.S., 2011 – 2021 124
Chart 5 37: Total Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 126
Chart 5 38: Synthetic Bone Graft Substitute Market by Indication, U.S., 2011 – 2021 127
Chart 5 39: Spine Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 128
Chart 5 40: Cervical Spine Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 129
Chart 5 41: Thoracolumbar Spine Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 130
Chart 5 42: Trauma Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 131
Chart 5 43: Non-union Trauma Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 132
Chart 5 44: Fresh Fracture Trauma Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 133
Chart 5 45: Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 134
Chart 5 46: Hip Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S.,
2011 – 2021 135
Chart 5 47: Knee Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S.,
2011 – 2021 136
Chart 5 48: Foot Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 137
Chart 5 49: Craniomaxillofacial Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 138
Chart 5 50: Oncology Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 139
Chart 5 51: Spine Bone Graft Substitute Market, U.S., 2011 – 2021 141
Chart 5 52: Cervical Spine Bone Graft Substitute Market, U.S., 2011 – 2021 143
Chart 5 53: Thoracolumbar Spine Bone Graft Substitute Market, U.S., 2011 – 2021 145
Chart 5 54: Trauma Bone Graft Substitute Market, U.S., 2011 – 2021 147
Chart 5 55: Non-union Trauma Bone Graft Substitute Market, U.S., 2011 – 2021 148
Chart 5 56: Fresh Fracture Trauma Bone Graft Substitute Market, U.S., 2011 – 2021 149
Chart 5 57: Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2011 – 2021 151
Chart 5 58: Hip Reconstruction Bone Graft Substitute Market, U.S., 2011 – 2021 152
Chart 5 59: Knee Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2011 – 2021 153
Chart 5 60: Foot Reconstruction Bone Graft Substitute Market, U.S., 2011 – 2021 155
Chart 5 61: Craniomaxillofacial Bone Graft Substitute Market, U.S., 2011 – 2021 157
Chart 5 62: Oncology Bone Graft Substitute Market, U.S., 2011 – 2021 159
Chart 5 63: Leading Competitors, Orthopedic Bone Graft Substitute Market, U.S., 2014 171
Chart 6 1: Orthopedic Growth Factor Market, U.S., 2011 – 2021 176
Chart 6 2: Leading Competitors, Orthopedic Growth Factor Market, U.S., 2014 181
Chart 7 1: Orthopedic Stem Cell Market by Anatomy, U.S., 2011 – 2021 186
Chart 7 2: Total Orthopedic Stem Cell Market, U.S., 2011 – 2021 188
Chart 7 3: Cervical Spine Stem Cell Market, U.S., 2011 – 2021 189
Chart 7 4: Lumbar Spine Stem Cell Market, U.S., 2011 – 2021 190
Chart 7 5: Leading Competitors, Orthopedic Stem Cell Market, U.S., 2014 196
Chart 8 1: Orthopedic Cell Therapy Market by Segment, U.S., 2011 – 2021 201
Chart 8 2: Orthopedic Cell Therapy Market Breakdown, U.S., 2014 202
Chart 8 3: Orthopedic Cell Therapy Market Breakdown, U.S., 2021 202
Chart 8 4: Total Platelet-Rich Plasma Market, U.S., 2011 – 2021 204
Chart 8 5: Soft Tissue Platelet-Rich Plasma Market, U.S., 2011 – 2021 205
Chart 8 6: Orthopedic Platelet-Rich Plasma Market, U.S., 2011 – 2021 206
Chart 8 7: Cardiac Platelet-Rich Plasma Market, U.S., 2011 – 2021 207
Chart 8 8: Spine Platelet-Rich Plasma Market, U.S., 2011 – 2021 208
Chart 8 9: Plastics Platelet-Rich Plasma Market, U.S., 2011 – 2021 209
Chart 8 10: Total Bone Marrow Concentrate Market, U.S., 2011 – 2021 211
Chart 8 11: Spine Bone Marrow Concentrate Market, U.S., 2011 – 2021 212
Chart 8 12: Trauma Bone Marrow Concentrate Market, U.S., 2011 – 2021 213
Chart 8 13: Soft Tissue Bone Marrow Concentrate Market, U.S., 2011 – 2021 214
Chart 8 14: Joint Reconstruction Bone Marrow Concentrate Market, U.S., 2011 – 2021 215
Chart 8 15: Leading Competitors, Orthopedic Cell Therapy Market, U.S., 2014 220
Chart 9 1: Orthopedic Hyaluronic Acid Viscosupplementation Market by Segment, U.S.,
2011 – 2021 227
Chart 9 2: Orthopedic Hyaluronic Acid Viscosupplementation Market Breakdown, U.S., 2014 228
Chart 9 3: Orthopedic Hyaluronic Acid Viscosupplementation Market Breakdown, U.S., 2021 228
Chart 9 4: Single-Injection Hyaluronic Acid Viscosupplementation Market, U.S., 2011 – 2021 232
Chart 9 5: Three-Injection Hyaluronic Acid Viscosupplementation Market, U.S., 2011 – 2021 234
Chart 9 6: Five-Injection Hyaluronic Acid Viscosupplementation Market, U.S., 2011 – 2021 236
Chart 9 7: Leading Competitors, Orthopedic Hyaluronic Acid Viscosupplementation Market, U.S.,
2014 242
Chart 10 1: Orthopedic Cartilage Repair Market by Segment, U.S., 2011 – 2021 247
Chart 10 2: Orthopedic Cartilage Repair Market Breakdown, U.S., 2014 248
Chart 10 3: Orthopedic Cartilage Repair Market Breakdown, U.S., 2021 248
Chart 10 4: Osteochondral Allograft Market, U.S., 2011 – 2021 250
Chart 10 5: Meniscal Allograft Market, U.S., 2011 – 2021 252
Chart 10 6: Autologous Chondrocyte Implantation Market, U.S., 2011 – 2021 254
Chart 10 7: Particulated Juvenile Allograft Implant Market, U.S., 2011 – 2021 256
Chart 10 8: Microfracture Adjunct Market, U.S., 2011 – 2021 258
Chart 10 9: Leading Competitors, Orthopedic Cartilage Repair Market, U.S., 2014 264
Chart 11 1: Spinal Machined Bone Allograft Market by Segment, U.S., 2011 – 2021 269
Chart 11 2: Spinal Machined Bone Allograft Market Breakdown, U.S., 2014 270
Chart 11 3: Spinal Machined Bone Allograft Market Breakdown, U.S., 2021 270
Chart 11 4: Total Spinal Machined Bone Allograft Market, U.S., 2011 – 2021 273
Chart 11 5: ALIF Machined Bone Allograft Market, U.S., 2011 – 2021 275
Chart 11 6: PLIF Machined Bone Allograft Market, U.S., 2011 – 2021 277
Chart 11 7: TLIF Machined Bone Allograft Market, U.S., 2011 – 2021 279
Chart 11 8: CIF Machined Bone Allograft Market, U.S., 2011 – 2021 281
Chart 11 9: Leading Competitors, Spinal Machined Bone Allograft Market, U.S., 2014 288



LIST OF FIGURES
Figure 3 1: Orthopedic Biomaterials Market by Segment, U.S., 2011 – 2021 (US$M) 29
Figure 3 2: Orthopedic Biomaterials Market Growth by Segment, U.S., 2011 – 2021 33
Figure 3 3: Drivers and Limiters, Orthopedic Biomaterials Market, U.S., 2014 37
Figure 3 4: Leading Competitors, Orthopedic Biomaterials Market, U.S., 2014 (Part 1 of 2) 43
Figure 3 5: Leading Competitors, Orthopedic Biomaterials Market, U.S., 2014 (Part 2 of 2) 44
Figure 3 6: Herfindahl Index, Orthopedic Biomaterials Market, U.S., 2014 46
Figure 4 1: Bone Graft Procedure Numbers By Type, U.S., 2011 – 2021 55
Figure 4 2: Bone Graft Substitute Procedure Numbers by Material, U.S., 2011 – 2021 57
Figure 4 3: Bone Graft Substitute Procedure Numbers by Indication, U.S., 2011 – 2021 59
Figure 4 4: Growth Factor Bone Graft Procedure Numbers, U.S., 2011 – 2021 61
Figure 4 5: Stem Cell Bone Graft Procedure Numbers, U.S., 2011 – 2021 63
Figure 4 6: Cell Therapy Treatment Numbers by Type, U.S., 2011 – 2021 65
Figure 4 7: Platelet-Rich Plasma Treatment Numbers By Indication, U.S., 2011 – 2021 67
Figure 4 8: Bone Marrow Concentrate Treatment Numbers By Indication, U.S., 2011 – 2021 68
Figure 4 9: Hyaluronic Acid Treatment Numbers By Type, U.S., 2011 – 2021 69
Figure 4 10: Cartilage Repair Procedure Numbers By Type, U.S., 2011 – 2021 72
Figure 4 11: Spinal Machined Bone Allograft Procedure Numbers by Approach, U.S., 2011 – 2021 74
Figure 5 1: Bone Graft Substitute Procedure Numbers By Material, U.S., 2011 – 2021 81
Figure 5 2: Units per Procedure by Indication, Bone Graft Substitute Market, U.S., 2011 – 2021 83
Figure 5 3: Orthopedic Bone Graft Substitute Market by Material, U.S., 2011 – 2021 (US$M) 85
Figure 5 4: Orthopedic Bone Graft Substitute Market by Indication, U.S., 2011 – 2021 (US$M) 89
Figure 5 5: Total Orthopedic Bone Graft Substitute Market, U.S., 2011 – 2021 92
Figure 5 6: Total Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 95
Figure 5 7: Allograft Bone Graft Substitute Market by Indication, U.S., 2011 – 2021 (US$M) 96
Figure 5 8: Total Spine Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 97
Figure 5 9: Cervical Spine Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 98
Figure 5 10: Thoracolumbar Spine Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 99
Figure 5 11: Total Trauma Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 100
Figure 5 12: Non-union Trauma Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 101
Figure 5 13: Fresh Fracture Trauma Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 102
Figure 5 14: Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 103
Figure 5 15: Hip Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S.,
2011 – 2021 104
Figure 5 16: Knee Large Joint Reconstruction Allograft Bone Graft Substitute Market, U.S.,
2011 – 2021 105
Figure 5 17: Foot Reconstruction Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 106
Figure 5 18: Craniomaxillofacial Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 107
Figure 5 19: Oncology Allograft Bone Graft Substitute Market, U.S., 2011 – 2021 108
Figure 5 20: Total Demineralized Bone Matrix Market, U.S., 2011 – 2021 110
Figure 5 21: Demineralized Bone Matrix Market (with Carriers), U.S., 2011 – 2021 111
Figure 5 22: Demineralized Bone Matrix Market (without Carriers), U.S., 2011 – 2021 111
Figure 5 23: Demineralized Bone Matrix Market by Indication, U.S., 2011 – 2021 (US$M) 112
Figure 5 24: Spine Demineralized Bone Matrix Market, U.S., 2011 – 2021 113
Figure 5 25: Cervical Spine Demineralized Bone Matrix Market, U.S., 2011 – 2021 114
Figure 5 26: Thoracolumbar Spine Demineralized Bone Matrix Market, U.S., 2011 – 2021 115
Figure 5 27: Trauma Demineralized Bone Matrix Market, U.S., 2011 – 2021 116
Figure 5 28: Non-union Trauma Demineralized Bone Matrix Market, U.S., 2011 – 2021 117
Figure 5 29: Fresh Fracture Trauma Demineralized Bone Matrix Market, U.S., 2011 – 2021 118
Figure 5 30: Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2011 – 2021 119
Figure 5 31: Hip Large Joint Reconstruction Demineralized Bone Matrix Market, U.S., 2011 – 2021 120
Figure 5 32: Knee Large Joint Reconstruction Demineralized Bone Matrix Market, U.S.,
2011 – 2021 121
Figure 5 33: Foot Reconstruction Demineralized Bone Matrix Market, U.S., 2011 – 2021 122
Figure 5 34: Craniomaxillofacial Demineralized Bone Matrix Market, U.S., 2011 – 2021 123
Figure 5 35: Oncology Demineralized Bone Matrix Market, U.S., 2011 – 2021 124
Figure 5 36: Total Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 126
Figure 5 37: Synthetic Bone Graft Substitute Market by Indication, U.S., 2011 – 2021 (US$M) 127
Figure 5 38: Spine Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 128
Figure 5 39: Cervical Spine Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 129
Figure 5 40: Thoracolumbar Spine Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 130
Figure 5 41: Trauma Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 131
Figure 5 42: Non-union Trauma Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 132
Figure 5 43: Fresh Fracture Trauma Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 133
Figure 5 44: Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 134
Figure 5 45: Hip Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S.,
2011 – 2021 135
Figure 5 46: Knee Large Joint Reconstruction Synthetic Bone Graft Substitute Market, U.S.,
2011 – 2021 136
Figure 5 47: Foot Reconstruction Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 137
Figure 5 48: Craniomaxillofacial Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 138
Figure 5 49: Oncology Synthetic Bone Graft Substitute Market, U.S., 2011 – 2021 139
Figure 5 50: Spine Bone Graft Substitute Market, U.S., 2011 – 2021 140
Figure 5 51: Cervical Spine Bone Graft Substitute Market, U.S., 2011 – 2021 142
Figure 5 52: Thoracolumbar Spine Bone Graft Substitute Market, U.S., 2011 – 2021 144
Figure 5 53: Trauma Bone Graft Substitute Market, U.S., 2011 – 2021 146
Figure 5 54: Non-union Trauma Bone Graft Substitute Market, U.S., 2011 – 2021 148
Figure 5 55: Fresh Fracture Trauma Bone Graft Substitute Market, U.S., 2011 – 2021 149
Figure 5 56: Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2011 – 2021 150
Figure 5 57: Hip Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2011 – 2021 152
Figure 5 58: Knee Large Joint Reconstruction Bone Graft Substitute Market, U.S., 2011 – 2021 153
Figure 5 59: Foot Reconstruction Bone Graft Substitute Market, U.S., 2011 – 2021 154
Figure 5 60: Craniomaxillofacial Bone Graft Substitute Market, U.S., 2011 – 2021 156
Figure 5 61: Oncology Bone Graft Substitute Market, U.S., 2011 – 2021 158
Figure 5 62: Drivers and Limiters, Orthopedic Bone Graft Substitute Market, U.S., 2014 164
Figure 5 63: Leading Competitors, Orthopedic Bone Graft Substitute Market by Segment, U.S.,
2014 170
Figure 6 1: Orthopedic Growth Factor Market, U.S., 2011 – 2021 175
Figure 6 2: Drivers and Limiters, Orthopedic Growth Factor Market, U.S., 2014 179
Figure 6 3: Leading Competitors, Orthopedic Growth Factor Market, U.S., 2014 181
Figure 7 1: Orthopedic Stem Cell Market by Anatomy, U.S., 2011 – 2021 (US$M) 185
Figure 7 2: Total Orthopedic Stem Cell Market, U.S., 2011 – 2021 188
Figure 7 3: Cervical Spine Stem Cell Market, U.S., 2011 – 2021 189
Figure 7 4: Lumbar Spine Stem Cell Market, U.S., 2011 – 2021 190
Figure 7 5: Drivers and Limiters, Orthopedic Stem Cell Market, U.S., 2014 193
Figure 7 6: Leading Competitors, Orthopedic Stem Cell Market, U.S., 2014 195
Figure 8 1: Orthopedic Cell Therapy Market by Segment, U.S., 2011 – 2021 (US$M) 200
Figure 8 2: Total Platelet-Rich Plasma Market, U.S., 2011 – 2021 204
Figure 8 3: Soft Tissue Platelet-Rich Plasma Market, U.S., 2011 – 2021 205
Figure 8 4: Orthopedic Platelet-Rich Plasma Market, U.S., 2011 – 2021 206
Figure 8 5: Cardiac Platelet-Rich Plasma Market, U.S., 2011 – 2021 207
Figure 8 6: Spine Platelet-Rich Plasma Market, U.S., 2011 – 2021 208
Figure 8 7: Plastics Platelet-Rich Plasma Market, U.S., 2011 – 2021 209
Figure 8 8: Total Bone Marrow Concentrate Market, U.S., 2011 – 2021 211
Figure 8 9: Spine Bone Marrow Concentrate Market, U.S., 2011 – 2021 212
Figure 8 10: Trauma Bone Marrow Concentrate Market, U.S., 2011 – 2021 213
Figure 8 11: Soft Tissue Bone Marrow Concentrate Market, U.S., 2011 – 2021 214
Figure 8 12: Joint Reconstruction Bone Marrow Concentrate Market, U.S., 2011 – 2021 215
Figure 8 13: Drivers and Limiters, Orthopedic Cell Therapy Market, U.S., 2014 217
Figure 8 14: Leading Competitors, Orthopedic Cell Therapy Market, U.S., 2014 220
Figure 9 1: Orthopedic Hyaluronic Acid Viscosupplementation Market by Segment, U.S.,
2011 – 2021 (US$M) 226
Figure 9 2: Total Hyaluronic Acid Viscosupplementation Market, U.S., 2011 – 2021 229
Chart 9 3: Total Hyaluronic Acid Viscosupplementation Market, U.S., 2011 – 2021 230
Figure 9 4: Single-Injection Hyaluronic Acid Viscosupplementation Market, U.S., 2011 – 2021 231
Figure 9 5: Three-Injection Hyaluronic Acid Viscosupplementation Market, U.S., 2011 – 2021 233
Figure 9 6: Five-Injection Hyaluronic Acid Viscosupplementation Market, U.S., 2011 – 2021 235
Figure 9 7: Drivers and Limiters, Orthopedic Hyaluronic Acid Viscosupplementation Market, U.S.,
2014 239
Figure 9 8: Leading Competitors, Orthopedic Hyaluronic Acid Viscosupplementation Market, U.S.,
2014 242
Figure 10 1: Orthopedic Cartilage Repair Market by Segment, U.S., 2011 – 2021 (US$M) 246
Figure 10 2: Osteochondral Allograft Market, U.S., 2011 – 2021 249
Figure 10 3: Meniscal Allograft Market, U.S., 2011 – 2021 251
Figure 10 4: Autologous Chondrocyte Implantation Market, U.S., 2011 – 2021 253
Figure 10 5: Particulated Juvenile Allograft Implant Market, U.S., 2011 – 2021 255
Figure 10 6: Microfracture Adjunct Market, U.S., 2011 – 2021 257
Figure 10 7: Drivers and Limiters, Orthopedic Cartilage Repair Market, U.S., 2014 260
Figure 10 8: Leading Competitors, Orthopedic Cartilage Repair Market, U.S., 2014 263
Figure 11 1: Spinal Machined Bone Allograft Market by Segment, U.S., 2011 – 2021 (US$M) 268
Figure 11 2: Total Spinal Machined Bone Allograft Market, U.S., 2011 – 2021 272
Figure 11 3: ALIF Machined Bone Allograft Market, U.S., 2011 – 2021 274
Figure 11 4: PLIF Machined Bone Allograft Market, U.S., 2011 – 2021 276
Figure 11 5: TLIF Machined Bone Allograft Market, U.S., 2011 – 2021 278
Figure 11 6: CIF Machined Bone Allograft Market, U.S., 2011 – 2021 280
Figure 11 7: Drivers and Limiters, Spinal Machined Bone Allograft Market, U.S., 2014 285
Figure 11 8: Leading Competitors, Spinal Machined Bone Allograft Market, U.S., 2014 287



【掲載企業】

Medtronic
Genzyme
DePuy Synthes
Anika Therapeutics
Ferring Pharmaceuticals
Stryker
NuVasive
Bioventus
Biomet
Integra LifeSciences
RTI Surgical
MTF
Fidia Pharmaceuticals
Orthofix
Zimmer
Artrhex
Allosource
Exactech
Aastrom
Baxter
Harvest
Wright Medical


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