I. IntroductionII. Worldwide Market and Technology Overview
A. Background
B. Hepatitis A
C. Hepatitis B
D. Hepatitis C
0 Classification
0 Transmission of Infection
0 Occupational Hazards
0 Acute Hepatitis
0 Diagnosis of Acute Infection
0 Chronic Hepatitis
0 HCV and Other Chronic Liver Diseases
0 Alcoholic Liver Disease
0 Hepatitis B Coinfection
0 Cirrhosis and Hepatocellular Carcinoma
0 Diagnostic Tests
0 Possible Indications for HCV RNA Testing
0 Conclusions and Future Direction
E. Hepatitis D
0 Historical Perspective
0 Epidemiology
0 HBV-HDV “Coinfection” vs. “Superinfection”
0 Methods of Detecting HDV
0 Prevention
F. Hepatitis E
0 Background
0 Prevalence of the Disease
0 Diagnostic Tests
0 Epidemiologic Serosurveys
0 Serologic Cross-Reactivity
G. Hepatitis G
0 Vaccines and Drugs
H. Instrumentation Review and Market Needs
0 Abbott AxSYM
0 Abbott IMx/IMx Select
0 Anagen AN2000/AuraFlex
0 Beckman Coulter Access
0 BioChem Pharma/SR1
0 BioMerieux/Vitek Vidas
0 Biotrol System 7000
0 Chiron ACS: Centaur
0 Chiron ACS: 180
0 J&J Diagnostics/Amersham Amerlite
0 J&J Diagnostics Vitros ECi
0 Olympus PK310
0 Roche Cobas Core
0 Roche Elecsys 1010/2010
0 Roche ES 22
0 Roche ES 33
0 Roche ES 300/300AL
0 Siemens ELISA Processor II/III
0 Siemens Immuno 1
0 Siemens/Opus/Plus/Magnum
0 Siemens Stratus
0 Tosoh AIA-1200/1200DX/NexIA/600
0 Wallac/Pharmacia Delfia
I. Emerging Diagnostic Technologies
1. DNA Probes
a. Technology Overview
b. Amplification Methods
0 Polymerase Chain Reaction
- Robotics
- Temperature Cyclers
- PCR Variations
0 Immuno-PCR
0 QC-PCR
0 DAP-PCR
0 Ligase Chain Reaction
0 Branched DNA
0 Q-Beta Replicase
0 Nucleic-Acid Sequence-Based
0 Strand Displacement Activation
0 Self-Sustained Sequence Replicase
2. Monoclonal Antibodies
3. Immunoassays
a. Technological Principle
b. Enzyme Immunoassays (EIA)
0 Overview
0 ELISA
0 Dot Immunobinding Assays
0 Capillary Immunoassays
0 Particle-Membrane Capture Immunoassays
0 Enzyme Amplification
c. Fluorescent Immunoassays
0 Fluorescence Polarization
0 Time-Resolved Pulse Fluorescence
d. Luminescence
0 Chemiluminescence
0 Bioluminescence
e. Latex Agglutination
f. Immunoprecipitation
4. Differential Light Scattering
5. Microcomputers and Automation
6. Artificial Intelligence
7. Liposomes
8. Flow Cytometry
9. Chromatography
10. MRI
11. Gel Microdroplets
12. Other
III. France: Market Size, Growth and Major Suppliers’ Sales
and Market Shares
IV. Germany: Market Size, Growth and Major Suppliers’ Sales
and Market Shares
V. Italy: Market Size, Growth and Major Suppliers’ Sales
and Market Shares
VI. Japan: Market Size, Growth and Major Suppliers’ Sales
and Market Shares
VII. Spain: Market Size, Growth and Major Suppliers’ Sales
and Market Shares
VIII. UK: Market Size, Growth and Major Suppliers’ Sales
and Market Shares
IX. USA: Market Size, Growth and Major Suppliers’ Sales
and Market Shares
X. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies for Decentralized
Testing Markets
1. Marketing Approaches
2. Product Complexity
3. Customer Preference
4. Established Suppliers
5. Emerging Suppliers
6. Major Types of Distributors
7. Market Segmentation
XI. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges
XII. Competitive Assessments
– Abbott
- Affymetrix
- Applera
- Beckman Coulter
- Becton Dickinson
- Binding Site
- Biomerica
- Biokit
- bioMerieux
- Bio-Rad
- Biotrol
- Biosite
- Biotest
- Caliper Technologies
- Cepheid
- Chemicon
- Daiichi
- DiaSorin
- Diagast
- Diamedix
- Digene
- Eiken
- Enzo Biochem
- Fujirebio
- GenBio
- Gene-Tec
- Hemagen
- Immunetics
- Innogenetics
- Inverness
- J&J
- Meridian
- Nanogen
- Nissui
- Olympus
- Provalis
- Roche
- Saliva Diagnostic
- SeraCare
- Siemens
- Third Wave Technologies
- Thermo Fisher
- Tosho
- Trinity Biotech
- Tropix
- Wampole Labs
- Zenith
- Zeus
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